Plain-English translation of NCT06752798 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a medication called trilaciclib to protect your bone marrow (where blood cells are made) while you receive chemotherapy for advanced head and neck cancer. Trilaciclib has already been approved by the FDA to help protect bone marrow in other cancer patients. This study will see whether it works the same way for people with head and neck cancer who are getting chemotherapy combined with radiation after surgery.
Chemotherapy is a powerful treatment that kills cancer cells, but it can also damage the healthy cells in your bone marrow that make blood cells—which can cause serious side effects like infections and fatigue. Researchers want to know if this medication can reduce that damage and help you tolerate your cancer treatment better.
You likely qualify if…
You likely don't qualify if…
You would receive the protective medication as an intravenous infusion (through an IV) over 30 minutes, given just before each chemotherapy session. You would then receive chemotherapy once a week for 6 to 7 weeks, along with radiation therapy. The study involves 30 patients total, and you would be monitored closely with blood tests and clinical visits to see how well the protective medication works and how you tolerate the combined treatment.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
China
Phase
Testing effectiveness
Sponsor
Hunan Cancer Hospital
Enrollment target
~30 participants
Started
December 2024
Primary completion
September 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in December 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Feng Liu, Doctoral Degree
Hunan Cancer Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.