Plain-English translation of NCT06754709 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying how certain proteins in the blood and heart change during heart surgery in children, particularly when a heart-lung machine (called extracorporeal circulation) is used to support the child during the operation. The goal is to understand why some children develop serious complications after surgery — like heart weakness, fluid buildup in tissues, and organ stress — and to identify new ways to prevent or treat these problems.
Heart surgery with a heart-lung machine can trigger a serious inflammatory response in the body that leads to dangerous complications in many children within hours after surgery. By studying how proteins change during and after this type of surgery, researchers hope to find new targets for treatment that could prevent these life-threatening complications.
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If your child is enrolled, extra blood samples will be taken at the same times blood is already being drawn as part of routine heart surgery care — so no additional needle sticks. If a small piece of heart tissue is being removed during surgery anyway, researchers may preserve it for study. After surgery, your child will be monitored as usual, and doctors will collect information from the medical record. There are no extra visits or procedures beyond standard surgical care.
AI-generated summary from trial data · Sep 17, 2026 · Not medical advice
France