Plain-English translation of NCT06755372 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand why people with end-stage kidney failure (when kidneys stop working and patients need dialysis) often develop severe gum disease. This study will compare gum health and immune system markers in 50 people with healthy kidneys who have gum disease and 50 people with kidney failure who also have gum disease, all living in Egypt.
Kidney disease and gum disease appear to be connected, and gum disease may worsen kidney function and overall health in kidney failure patients. This study aims to understand this relationship better by looking at a specific immune system protein called Toll-like Receptor-4, which may explain why these two conditions occur together.
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If you join this study, you will have your teeth and gums examined by dental professionals who will measure plaque, gum bleeding, pocket depth, and other signs of gum health. Blood samples may be taken to measure immune system markers. The study compares two groups—those with healthy kidneys and those on dialysis—to understand how kidney disease affects gum disease. Participation is observational, meaning you will not receive new treatment, but your information helps researchers understand this important health connection.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Egypt
Sponsor
Ain Shams University
Enrollment target
~100 participants
Started
April 2025
Primary completion
July 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
30 Years – 60 Years
Last updated on clinicaltrials.gov in July 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Asmaa Bakr elshaf3y, PHD
king Salman Intwenational University University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.