Plain-English translation of NCT06756009 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are investigating whether detailed images of the back of your eye can help doctors better understand how severe your liver disease is and predict how well a liver transplant might work for you. The study will compare eye imaging results in three groups: patients waiting for or who have had a liver transplant, and healthy people without liver disease. The goal is to develop a tool that uses these eye images alongside blood tests and imaging to give doctors better information about your liver health.
Doctors currently rely on blood tests and imaging scans to assess liver disease, but these tests don't always give a complete picture of how sick someone is or how well they'll do after a transplant. This research explores whether eye imaging—which can show very detailed blood vessel and tissue changes—might provide additional helpful information that could improve transplant planning and outcomes.
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If you're in the transplant group, you would have eye imaging scans done before your transplant surgery and then again after surgery during follow-up visits. If you're in the post-transplant group, you would have eye scans during regular follow-up appointments after your transplant. Healthy volunteers would come in for eye imaging one time. The eye scans are painless, non-invasive tests that take pictures of the blood vessels and tissue in the back of your eye—similar to how an ultrasound works, but using light instead.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
China
Sponsor
Zhongshan Ophthalmic Center, Sun Yat-sen University
Collaborators
First Affiliated Hospital, Sun Yat-Sen University, Second Affiliated Hospital, Sun Yat-Sen University
Enrollment target
~500 participants
Started
March 2022
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in January 2025.
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Central contact
Zizheng Cao, M.D.
Zhongshan Ophthalmic Center, Sun Yat-sen University
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