Plain-English translation of NCT06758375 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing whether a newer medication called teclistamab can help people with newly diagnosed multiple myeloma get better results when used after standard chemotherapy. You would first receive three cycles of standard chemotherapy drugs (bortezomib, lenalidomide, and dexamethasone), then receive the medication as a follow-up treatment. The goal is to see if this approach is safe and effective at controlling the cancer long-term.
Multiple myeloma is a serious blood cancer, and doctors are always looking for better ways to treat it, especially in newly diagnosed patients. This trial exists to see whether adding this medication after standard chemotherapy can improve how well the cancer responds and how long people stay in remission.
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You would start by receiving three cycles of standard chemotherapy drugs over several months. After that, you would receive four doses of the new medication as injections under the skin, spaced over several weeks. About four weeks after your last dose, you would have blood tests and scans to see how well the treatment worked. Depending on your response, you may continue with additional monitoring or maintenance treatment for up to 18 months total.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
Mexico
Phase
Testing effectiveness
Sponsor
Hospital Universitario Dr. Jose E. Gonzalez
Enrollment target
~10 participants
Started
March 2025
Primary completion
September 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2025.
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Central contact
David Gomez-Almaguer, MD
Hospital Universitario Dr. Jose E. Gonzalez
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