Plain-English translation of NCT06758609 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
When someone has a large blood clot blocking blood flow to the brain, doctors perform emergency surgery to remove it. This trial is testing whether adding a cooling technique—using chilled saline (salt water) delivered through a catheter to cool the brain during surgery—can improve recovery compared to standard surgery alone. The cooling is thought to protect brain tissue and reduce damage while blood flow is being restored.
Large stroke clots cause serious brain damage very quickly because brain cells die without oxygen. Even after doctors successfully remove the clot, the brain can continue to be injured. This trial is testing whether cooling the brain during this critical time might reduce damage and help patients recover better function.
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If you qualify and enroll, you will be randomly assigned to receive either the cooling treatment or standard surgery without cooling. Both groups receive the same emergency blood clot removal surgery. The only difference is whether the saline used during surgery is chilled (350 ml of cold salt water) or room temperature. You will then be monitored closely in the hospital and have follow-up visits to track your recovery and brain function.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
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