Testing two medications to reduce brain swelling after bleeding stroke

This study is testing whether two medications—deferoxamine and colchicine—can help people recover better after a sudden bleed in the brain (intracerebral hemorrhage). One medication targets iron-related damage, while the other reduces harmful inflammation. Researchers will randomly assign participants to receive standard care alone, one of these medications, or both together, then track how well people recover over six months.

Bleeding strokes are severe and often leave survivors with lasting disability, cognitive problems, and depression. Currently, there are very few proven treatments that specifically reduce the brain swelling and secondary damage that happens after this type of stroke, so this trial is testing whether these medications can fill that gap.