Plain-English translation of NCT06764966 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether atorvastatin, a common cholesterol medication, can help people with advanced liver cirrhosis when added to their current treatment. Right now, doctors are unsure whether this medication is safe and helpful for liver patients, even though early research suggests it might reduce liver disease worsening. The study will follow 50 people for one year to see if the combination treatment works better than current care alone.
Advanced liver cirrhosis causes serious complications like internal bleeding, belly swelling, and confusion, and there aren't many treatment options available. While the medication being tested has been used safely in other patients, doctors have historically avoided it in liver disease out of caution. This trial will help determine whether adding this treatment to standard care could slow disease progression and prevent life-threatening complications.
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If you join this study, you will be randomly assigned to take either the new medication or a placebo pill once daily, along with your current beta-blocker. You will visit the liver clinic at the study hospital regularly over 12 months so doctors can check how you're doing, monitor your liver function, and watch for any side effects. The study team will track whether the medication helps reduce complications and improves your health outcomes.
AI-generated summary from trial data · Jun 15, 2026 · Not medical advice
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