Two ways to lower cholesterol and stabilize heart plaques

This trial is testing whether taking a moderate dose of Rosuvastatin combined with Ezetimibe works as well as taking a higher dose of Rosuvastatin alone at stabilizing plaque in your coronary arteries. Both are cholesterol-lowering medications. Researchers will use special imaging to look inside your heart arteries and measure whether the plaque becomes more stable over one year.

When people have coronary artery disease, plaque builds up in their heart arteries and can become unstable, which increases the risk of a heart attack. Doctors want to know if combining two different medications at moderate doses might work just as well as a single higher-dose medication—which could mean fewer side effects for patients.