Plain-English translation of NCT06768138 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether adding a medication called Alteplase directly into a brain artery — after doctors have already successfully opened the blocked vessel — helps stroke patients recover better. The medication is delivered through a thin tube (catheter) that's already in place during emergency stroke treatment. Researchers want to know if this extra step improves how well patients function three months after their stroke.
Even after doctors successfully open a blocked artery in a stroke, some patients don't recover as well as hoped. Researchers believe that delivering this clot-dissolving medication directly to the problem area might help clear remaining clots and improve the brain's blood flow, leading to better long-term outcomes.
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If you join this trial, you'll be randomly assigned to either receive the additional medication or standard care alone, right after your emergency stroke treatment is complete — while you're still in the hospital's imaging suite. The study team will follow your recovery over three months with clinic visits and assessments to see how well you're functioning. Your main involvement happens during the acute emergency phase; afterward, you'll have regular follow-up appointments to check on your progress.
AI-generated summary from trial data · Jul 19, 2026 · Not medical advice
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