Plain-English translation of NCT06774365 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is looking for better ways to identify antibody-mediated rejection—a type of immune response that can damage a transplanted heart. Researchers will collect blood samples and use specialized imaging to find new signs that could help doctors catch this rejection earlier, before it causes serious harm. Your participation helps develop tools that could protect transplanted hearts long-term.
After a heart transplant, the body's immune system sometimes attacks the new heart in ways that are hard to detect with current tests. This study aims to find new blood markers and imaging patterns that could warn doctors about rejection sooner, giving them a chance to treat it before permanent damage occurs.
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You will come in for a study visit where researchers will draw blood samples for specialized testing in a centralized lab, along with routine clinical samples. This happens as part of your regular yearly antibody screening, which is standard care after transplant. The study team will also collect information about your medical history and recent test results, and the results from this study will not change your current treatment plan.
AI-generated summary from trial data · Jul 19, 2026 · Not medical advice
Italy
Sponsor
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Collaborators
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, Azienda Ospedaliera dei Colli
Enrollment target
~683 participants
Started
November 2024
Primary completion
December 2029
Age range
18 Years and older
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Luciano Potena, MD
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.