Plain-English translation of NCT06779578 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing two different approaches using pulsed radiofrequency — a minimally invasive procedure that uses targeted heat to reduce nerve pain — in patients with severe, medication-resistant trigeminal neuralgia (a condition causing intense facial pain). You would be randomly assigned to receive either a bipolar or monopolar pulsed radiofrequency procedure, and the researchers will track your pain relief and satisfaction over six months to see which approach works better.
Trigeminal neuralgia causes severe facial pain that can be difficult to control with medications alone. This trial exists to compare two different radiofrequency techniques to determine which one provides better and longer-lasting pain relief with fewer complications.
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You would come to the hospital for a one-time outpatient procedure under light sedation, where doctors use fluoroscopic guidance (live X-ray imaging) to carefully position a thin needle near your trigeminal nerve and deliver radiofrequency energy. After the procedure, you would return for follow-up visits at two weeks, one month, three months, and six months to report your pain levels, satisfaction with the treatment, and any side effects. Throughout the study, your pain relief will be tracked using a simple pain scale, and you may or may not need pain medications afterward depending on your results.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
Egypt
Sponsor
Alexandria University
Enrollment target
~20 participants
Started
January 2024
Primary completion
June 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Last updated on clinicaltrials.gov in January 2025.
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Central contact
Eman Hamdy, PhD
Alexandria University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.