Testing a fluorescent dye technique to improve breast cancer surgery

This trial is testing a new surgical technique that uses a fluorescent dye called indocyanine green (ICG) to help surgeons see and remove breast cancer tumors more accurately during breast-conserving surgery. Patients in this study will have advanced breast cancer that has been treated with chemotherapy, and they will receive surgery using this new imaging method. The goal is to make sure surgeons remove all of the cancer while preserving as much healthy breast tissue as possible.

After chemotherapy, it can be difficult for surgeons to find and remove the remaining tumor precisely because it may be hard to see or feel. The traditional methods used to locate tumors during surgery have limitations, especially in patients with larger breasts. This trial is testing whether the fluorescent dye technique can help surgeons locate and remove tumors more accurately than older methods.