Plain-English translation of NCT06781983 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This is an early-stage trial testing a new medication called in people with advanced cancer that has spread or cannot be surgically removed. The study is checking whether the medication is safe, how well people tolerate it, and whether it shows promise in slowing or shrinking tumors. The medication targets cancers that have a specific protein on their surface called Nectin-4.
Many people with advanced solid tumors run out of treatment options that work for their specific cancer type. This study exists to explore whether this new medication could become another option for patients who have already tried other therapies without success.
You would receive escalating doses of the medication at a clinical research center as part of the first phase, where doctors carefully monitor your safety and how your body tolerates the treatment. The study includes blood tests, imaging scans, and physical exams at various visits to check how the medication is working and watch for side effects. Depending on the results and which cancer types show promise, some patients may continue into a second phase to further test the best dose.
AI-generated summary from trial data · Jun 30, 2026 · Not medical advice
United States