Plain-English translation of NCT06782867 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing responsive neurostimulation (RNS)—a surgically implanted device that delivers targeted electrical pulses to specific areas of the brain—for people with treatment-resistant obsessive-compulsive disorder (OCD). About 4 in 10 people with OCD continue to struggle with symptoms even after trying multiple medications and therapy. This treatment aims to help those patients by using brain imaging to identify the best stimulation targets and monitoring when stimulation is needed.
Most current medications and therapy don't work well enough for a significant number of OCD patients. This trial exists to see whether this treatment can safely reduce symptoms in people who have already tried and failed multiple standard approaches, and to better understand how stimulating certain brain regions might help control obsessive and compulsive thoughts and behaviors.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will undergo surgery to have the stimulation device implanted in your brain, guided by specialized brain mapping to find the best targets for your individual brain. After surgery, the device will be activated to deliver stimulation, and you'll return for follow-up visits to monitor how well it's working and adjust settings as needed. Some participants may also be invited to complete optional additional brain imaging scans or cognitive tasks to help researchers understand how the treatment affects brain activity.
AI-generated summary from trial data · Jul 2, 2026 · Not medical advice
China
Sponsor
Xuanwu Hospital, Beijing
Enrollment target
~10 participants
Started
February 2025
Primary completion
December 2028
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in January 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Hongxing Wang, MD & PhD
Xuanwu Hospital, Beijing
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.