Plain-English translation of NCT06784765 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a newer technique called pressurized intraperitoneal aerosol chemotherapy (PIPAC) in people with advanced stomach cancer. The medication is delivered as an aerosol spray directly into the abdominal cavity during a minimally invasive procedure, which allows the chemotherapy drugs to reach cancer cells more effectively while causing less harm to your body than traditional methods. The study compares patients who receive this treatment before standard surgery and chemotherapy against those who receive standard treatment alone.
Stomach cancer often spreads to the lining of the abdomen after surgery, and this type of recurrence is very difficult to treat and associated with poor outcomes. Doctors hope that giving the medication early, before surgery, might prevent this spread and improve survival.
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If you are in the treatment group, you would first undergo a minimally invasive procedure to receive the aerosol chemotherapy into your abdomen. You would then receive standard chemotherapy (FLOT regimen) over several months before undergoing surgery to remove the stomach and surrounding lymph nodes. Throughout your participation, you would have regular clinic visits, scans, and blood tests to monitor how you are doing. The study will follow you after surgery to track whether the cancer returns and how well you are doing overall.
AI-generated summary from trial data · Jul 15, 2026 · Not medical advice
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