Plain-English translation of NCT06787183 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a new combination approach for rectal cancer that has spread to the liver. The study combines three types of treatment: chemotherapy (called CAPOX), radiation therapy, and a newer immunotherapy drug called . The goal is to see if using all three together works better than current standard approaches.
Rectal cancer that spreads to the liver is very difficult to treat, and current standard treatments don't work well enough for many patients. This trial is exploring whether combining radiation, chemotherapy, and immunotherapy—which harnesses your immune system to fight cancer—might offer a more powerful treatment option.
You likely qualify if…
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You would receive two rounds of chemotherapy combined with the immunotherapy drug, then have focused radiation therapy to your tumor, and finally two more rounds of chemotherapy with immunotherapy. The entire treatment would be given at a hospital or cancer center as part of a carefully planned schedule. You'll have regular visits for treatment, blood tests, and imaging scans to monitor how well the treatment is working and to watch for any side effects.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
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