Plain-English translation of NCT06787625 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are asking patients with colorectal cancer that has spread to the liver to donate tumor samples during surgery. These samples will be grown into small 3D models called organoids in the laboratory, where scientists can test how different genes work and find new ways to treat the cancer.
Colorectal cancer that spreads to the liver is hard to treat, and current treatments don't work for everyone. By growing tumors in the lab and testing them with immune cells from the same patient, researchers hope to discover new pathways that could lead to personalized medicines tailored to each patient's specific cancer.
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If you join this study, tissue samples from your colorectal tumor and liver metastasis will be collected during your scheduled cancer surgery—this doesn't require extra surgery or visits. The samples are then grown into organoids in the laboratory, where researchers study them over several months. You won't need to return for additional appointments related to the organoid work itself.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
Italy
Enrollment target
~10 participants
Started
May 2024
Primary completion
January 2028
Age range
18 Years and older
Last updated on clinicaltrials.gov in January 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Giulia Piaggio, Biologist
IRCCS National Cancer Institute
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.