Plain-English translation of NCT06789965 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is comparing two different surgical techniques designed to help people with moderate-to-severe obesity lose weight and improve their health. One approach, called SADI-S, combines stomach reduction with a bypass of part of the small intestine. The other, called Roux-en-Y gastric bypass, rearranges the digestive system in a different way. Researchers want to see which method helps people lose more weight and have better long-term results with fewer complications.
While surgery has been shown to be one of the most effective treatments for serious obesity, doctors are still trying to figure out which surgical approach works best for different patients. This trial exists to compare these two techniques head-to-head so doctors can offer patients the safest and most effective option.
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If you join this trial, you will be randomly assigned to receive one of the two surgical techniques. You'll undergo the surgery and then be followed by the research team to track your weight loss, improvement in related health conditions, and any side effects over time. The trial involves 450 participants total and will compare how well each technique works for you compared to the other group.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
Spain
Sponsor
Hospital Clinic of Barcelona
Enrollment target
~450 participants
Started
February 2025
Primary completion
August 2026
Age range
18 Years – 60 Years
Last updated on clinicaltrials.gov in May 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Javier Osorio, PhD
General & Digestive Surgery Department, ICMDM, Clinic Barcelona
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.