Plain-English translation of NCT06793397 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing a new medication called to see if it can help people with major depressive disorder who haven't fully responded to their current antidepressants. You would continue taking your regular antidepressant while also receiving this new medication in two sessions, about three weeks apart. Researchers want to understand how well this treatment works and whether it's safe and tolerable.
Many people with depression don't get enough relief from standard antidepressants alone. This trial exists to see if this medication, combined with the treatment you're already on, can provide better symptom relief for those who haven't fully benefited from their current medication.
You likely qualify if…
You likely don't qualify if…
You would visit the study clinic for two treatment sessions about three weeks apart, where you would receive either the new medication or a placebo (an inactive substance). Throughout the trial, you would continue taking your regular antidepressant and receive psychological support. The study team would monitor how you're doing through follow-up visits and assessments to measure any changes in your depression symptoms and check for side effects.
AI-generated summary from trial data · Sep 4, 2026 · Not medical advice
United States