Plain-English translation of NCT06794086 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Colorectal Cancer research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether combining two treatments—focused radiation therapy (SBRT) and a , an immunotherapy medication that helps your immune system fight cancer—works better together for colorectal cancer that has spread to the liver. You would also receive before and after the radiation. The goal is to see if this combination can shrink tumors, help people live longer, and improve quality of life.
Right now, some people with colorectal cancer spread to the liver cannot have surgery to remove it. Doctors want to know if pairing focused radiation with this medication might be a better option, since neither treatment alone has been fully proven for this specific situation.
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You would receive focused radiation therapy delivered in 5 sessions over about 2 weeks, with and the immunotherapy medication given before and after your radiation. About 8 weeks after radiation finishes, you would have imaging scans or possibly a liver biopsy to see how well the treatment worked. After that, your care team would decide whether you need more , observation only, or a different approach based on your response.
AI-generated summary from trial data · Jul 9, 2026 · Not medical advice
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