Plain-English translation of NCT06798714 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Coronary Artery Disease research guide →Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether colchicine, a medication that reduces inflammation, can help prevent a common heart rhythm problem called atrial fibrillation that sometimes develops after coronary artery bypass surgery. The study will also test a new surgical technique that involves a small procedure to help drain fluid from around the heart. Researchers want to see if using this medication combined with the new technique works better than standard care alone.
After bypass surgery, many patients develop irregular heart rhythms that can be serious and uncomfortable. This medication has anti-inflammatory properties that might help prevent this problem from occurring, but doctors need to test whether it actually works and is safe for heart surgery patients.
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If you join this study, you will receive bypass surgery as planned, but some participants will also receive the new surgical technique and colchicine medication starting 4 hours before surgery and continuing for 10 days afterward. Other participants will receive standard surgery and standard medications after surgery. Researchers will monitor you during your hospital stay after surgery to see whether you develop heart rhythm problems and will compare outcomes between the two groups.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
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