Plain-English translation of NCT06798844 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing spinal cord stimulation (a procedure where a small electrical device is placed near your spinal cord to send gentle electrical pulses) as a treatment for freezing of gait—a particularly disabling symptom of Parkinson's disease where people suddenly feel stuck and unable to move. Researchers noticed that some Parkinson's patients who received this electrical stimulation for pain also experienced fewer freezing episodes, which led them to study whether this treatment could help more people with this serious symptom.
Freezing of gait is one of the hardest symptoms of Parkinson's to treat—it often doesn't respond well to standard medications or other surgical treatments, and it causes falls, anxiety, and loss of independence. This trial exists because early observations suggest electrical spinal cord stimulation might help, but researchers need to conduct a rigorous study to confirm whether this treatment truly works and is safe.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will first receive a temporary spinal cord stimulation device (a thin wire placed near your spine connected to an external stimulator) for about 3 weeks so researchers can test whether this treatment helps your freezing and which settings work best for you. During this trial period, you will try two different stimulation settings and a sham (placebo) version to compare. If you experience meaningful improvement, you may then choose to have a permanent stimulation device surgically implanted. The study includes regular visits for assessments, walking tests, and detailed monitoring of your freezing episodes.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
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