Plain-English translation of NCT06800391 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether Capecitabine and Cyclophosphamide — two chemotherapy drugs taken as daily pills — can help patients with a rare abdominal cancer called pseudomyxoma peritonei shrink their tumors before surgery. The study focuses on patients with very advanced disease where the cancer has spread extensively throughout the abdomen. Researchers believe that giving this medication before surgery might make the operation less extensive and help patients recover better.
Patients with very advanced pseudomyxoma peritonei often need extremely complex surgery that can remove parts of the stomach or colon, leading to serious quality-of-life problems after surgery. This medication, given before surgery, may shrink the tumor enough to allow for less invasive surgery, reducing harm to the patient's body and improving their recovery.
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You would take two chemotherapy pills by mouth every day for 6 cycles, with each cycle lasting 28 days (about 6 months total). You will have regular clinic visits for blood tests and scans to monitor how the cancer is responding to the medication. After completing the medication cycles, if your tumor has shrunk enough, you would proceed to surgery and the heated chemotherapy treatment that is standard for your condition.
AI-generated summary from trial data · Aug 30, 2026 · Not medical advice
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