Plain-English translation of NCT06800430 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is investigating why saphenous vein grafts — veins taken from your leg and used to bypass blocked heart arteries during coronary artery bypass surgery — sometimes fail over time. Researchers want to understand the biological processes (inflammation, blood clotting, and scar tissue) that may lead to graft failure, so they can eventually develop better ways to prevent it.
Many patients who have coronary artery bypass surgery experience their vein grafts narrowing or closing years after surgery, which can cause symptoms and require additional treatment. Understanding exactly why this happens could help doctors develop new strategies to keep these grafts working longer.
You likely qualify if…
You likely don't qualify if…
If you're in the first group (having bypass surgery), you'll have blood tests, heart ultrasound, and advanced imaging scans soon after surgery and again at one year. If you're in the second group (with suspected graft problems), you'll have these same tests at one time point. All visits involve blood draws and non-invasive imaging — no additional surgery or medications are required.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
United Kingdom