Plain-English translation of NCT06800716 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →This research study is looking at how the Impella 5.5 — a small mechanical device that helps pump blood — may allow severely weakened hearts to heal and recover. Researchers will follow patients who receive this temporary support device while they wait for a heart transplant, collecting blood samples, heart imaging, and physical measurements to understand how and why some hearts improve.
Doctors have noticed that some patients with end-stage heart failure recover well enough on temporary mechanical support that they no longer need a transplant. This study aims to understand the biological mechanisms behind this recovery so doctors can better predict which patients might heal on their own.
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If you qualify, you will receive the Impella 5.5 device as part of your standard medical care while waiting for a transplant decision. Researchers will collect extra blood samples before and after device placement, perform heart imaging and measurements, and ask you to complete a 6-minute walking test and hand grip strength test. Over 14 days and potentially longer, doctors will monitor your heart's structure and function using ultrasound and blood work to see if your heart is healing.
AI-generated summary from trial data · Jul 10, 2026 · Not medical advice
United States