Plain-English translation of NCT06801392 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing whether different patterns of heart ablation—a procedure that uses energy to scar small areas of heart tissue—can effectively treat non-paroxysmal atrial fibrillation, which is a persistent irregular heartbeat. The study compares four different ablation strategies to see which pattern works best. Doctors will use new pulse field ablation technology to perform these procedures.
Current ablation procedures focus mainly on isolating the pulmonary veins, but doctors believe treating additional areas of the heart may improve results. This trial exists to determine the best pattern and approach for treating persistent irregular heartbeat and whether new ablation technology can achieve better long-term success.
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You will receive a heart ablation procedure where doctors insert catheters through blood vessels to reach your heart and apply energy to create scar tissue in specific patterns. The procedure tests one of four different ablation strategies to see which pattern most effectively controls your irregular heartbeat. You will be assigned to one of the four treatment groups, and your heart's response will be monitored to evaluate whether the ablation successfully treats your condition.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
Czechia
Sponsor
Charles University, Czech Republic
Collaborators
Biosense Webster, Inc.
Enrollment target
~50 participants
Started
January 2025
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in November 2025.
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Central contact
Pavel Osmancik, MD, PhD
Charles University, Czech Republic
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