Plain-English translation of NCT06801639 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Alzheimer Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a treatment called transcranial direct current stimulation (tDCS)—a non-invasive device that delivers mild electrical current to the brain through electrodes on the scalp. The study focuses on whether using this device at home for 30-minute sessions can help reduce mood and behavioral problems like depression, anxiety, irritability, or apathy that often accompany Alzheimer's disease. Half of the participants will receive active treatment, while the other half will receive a sham (placebo) version that looks and feels identical.
Many people with Alzheimer's disease experience emotional and behavioral changes that can be as distressing as memory problems, yet treatments for these symptoms are limited. Researchers want to see if this non-medication brain stimulation approach could offer a safe, drug-free way to improve quality of life for patients and their caregivers.
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You will have three in-person visits to the research clinic: one before treatment starts (for brain imaging and device training), one after the first treatment period, and one at the end of week five. Between visits, you'll use the tDCS device at home for 30-minute sessions over five weeks, with your caregiver present and the study team supervising remotely via video. You'll complete questionnaires about mood, thinking, and side effects, and undergo brain scans and electrical monitoring to help researchers understand how the treatment works.
AI-generated summary from trial data · Jul 1, 2026 · Not medical advice
United States