Recruiting

Testing a New Eczema Medicine for Children Ages 6 to 11

Plain-English translation of NCT06807268 on ClinicalTrials.gov ↗ · Source last updated May 2026 · Translation generated June 2026 · How we translate trials

Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.

What is this trial?

This 16-week study is testing a new medication called to see if it can help children ages 6 to 11 with moderate-to-severe eczema. Half of the participants will receive the medication as a liquid, while the other half will receive a placebo (a liquid that looks the same but has no active ingredient). The study will track how much the medication improves eczema symptoms and how safe it is for children.

Many children with severe eczema don't get enough relief from creams and topical treatments alone. Researchers want to find out if this new medication—which works differently than current treatments—could be a safe and effective option for children whose eczema isn't controlled with standard therapies.

Do you qualify?

You likely qualify if…

you are between 6 and 11 years old at the time you join
you have been diagnosed with eczema for at least 1 year
your eczema is moderate-to-severe and covers at least 10% of your body
you have tried topical eczema treatments (like creams) for at least 4 weeks without enough improvement
you weigh at least 15 kilograms (about 33 pounds)

You likely don't qualify if…

you have an active skin infection that needs antibiotics or had a skin infection in the past week
you have a serious infection history, including HIV, hepatitis B or C, or active tuberculosis
you have a history of certain skin conditions like psoriasis or lupus that would interfere with measuring eczema
you have had blood clotting problems, certain eye conditions, or a history of cancer
you have severe emotional or behavioral concerns that your doctor thinks might make it unsafe to participate

What participation looks like

You will visit the clinic several times over 16 weeks for check-ups, blood tests, and physical exams. Your child will take either the new medication or a placebo by mouth each day (the electronic device will remind you). You'll use a special wristwatch-like device that tracks scratching, fill out questionnaires about symptoms using a phone-like device, and answer questions from the research team during check-in calls between visits.

AI-generated summary from trial data · Jun 3, 2026 · Not medical advice

Trial locations(41 sites)

United States

Cahaba Dermatology & Skin Health Center, LLC, Birmingham, Alabama

Arkansas Research Trials, North Little Rock, Arkansas

Investigational Drug Service - Rady Childrens Hospital-San Diego, San Diego, California

University of California, San Diego/Rady Children's Hospital-San Diego; Pediatric & Adolescent Derm, San Diego, California

Solutions Through Advanced Research, Jacksonville, Florida