Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial

Recruiting

Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.

Trial locations(4 sites)

United States

UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine, California

UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California

Oregon Health and Science University, Portland, Oregon

University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania