Plain-English translation of NCT06814431 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is looking at whether Parkinson's disease patients with a specific genetic change in the GBA gene have different rates of cancer compared to those without this change. Researchers will collect information from about 3,000 Parkinson's disease patients across Italy and compare cancer cases between those with and without the GBA gene change. This will help doctors understand if genetic factors influence cancer risk in people with Parkinson's disease.
Some Parkinson's disease patients have a genetic variation that may affect their health in ways beyond movement symptoms. Doctors want to know if this genetic change is linked to higher cancer rates, so they can better monitor and care for these patients.
You likely qualify if…
You likely don't qualify if…
If you join this study, researchers will review your existing medical records to see if you have had any cancer diagnoses. You won't need to take any medication or undergo any new medical procedures — this is purely a data collection study. Your information will be matched with official cancer registry records to ensure accurate information.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
Italy
Enrollment target
~3,000 participants
Started
November 2023
Primary completion
December 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Giulia Di Rauso, MD
Azienda USL Reggio Emilia - IRCCS
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.