Plain-English translation of NCT06816056 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Hemophilia A research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a specific set of manual therapy techniques — hands-on physical treatments performed by a physiotherapist — to see if they can safely help people with hemophilia who have developed ankle joint damage. The study will compare patients who receive the active manual therapy treatment to patients who receive a placebo version (where the physiotherapist goes through the same hand positions and timing, but without the actual therapeutic techniques). Researchers want to see if this treatment can reduce pain, improve how well the ankle moves and functions, and help people feel more confident using their ankle.
Hemophilia-related ankle joint damage causes chronic pain, weakness, reduced movement, and balance problems that affect daily life. Right now, there aren't many proven treatment options beyond standard physiotherapy, so this trial is testing whether specialized manual therapy techniques could offer patients a safer, more effective way to manage these symptoms.
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If you join this trial, you will have an initial assessment, then be randomly assigned to either receive active manual therapy or placebo treatment. Over 3 weeks, you will attend one 50-minute session per week (3 sessions total) where a physiotherapist will perform various hands-on techniques on your ankle. You will be evaluated again right after the 3-week treatment period and then once more 4 weeks later to see if there have been any changes in your pain, ankle movement, strength, balance, and how well your ankle functions in daily life.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
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