Recruiting

Time-restricted eating and healthy diet for liver disease and cancer patients

Plain-English translation of NCT06824974 on ClinicalTrials.gov ↗ · Source last updated June 2026 · Translation generated July 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This is a feasibility study testing whether a lifestyle intervention combining time-restricted eating (stopping food intake by 7 PM and fasting for 14-16 hours overnight) and a healthy diet can be safely adopted by adults with metabolic liver disease or early-stage liver cancer. Researchers want to understand whether this eating pattern is practical for patients to follow, safe to try, and whether it improves blood markers related to metabolism, inflammation, and overall quality of life.

Many people with metabolic liver disease or liver cancer also struggle with obesity and metabolic problems. This trial explores whether time-restricted eating—a simpler dietary approach than counting calories—might help improve these conditions, reduce inflammation, and give patients better outcomes without requiring complex dietary restrictions.

Do you qualify?

You likely qualify if…

you are overweight or obese (BMI of 27 or higher)
you have been diagnosed with metabolic liver disease, fatty liver disease, liver inflammation, cirrhosis, or early-to-intermediate stage liver cancer
you are 18 years or older and speak English or Spanish
your current eating pattern involves less than 12 hours of fasting at night (meaning you typically eat late in the evening)
you are willing and able to participate in study visits and follow the eating schedule for the duration of the trial
you have a life expectancy of at least 12 months

You likely don't qualify if…

you have advanced liver cancer, cancer that has spread to other parts of your body, or fluid buildup in your abdomen
you have advanced cirrhosis of the liver with severe liver dysfunction
you have type 1 diabetes, a history of dangerously low blood sugar episodes, or experience frequent low blood sugar events
you have severe, uncontrolled eating disorders, disordered eating patterns, or food insecurity
you have been diagnosed with another cancer in the past 10 years (except skin cancer or cervical cancer in situ)

What participation looks like

If you join the intervention group, you will adopt a time-restricted eating schedule where you stop eating by 7 PM each night and fast for 14-16 hours before your next meal, while also following a healthy diet plan. If you are in the control group, you will continue your normal eating habits while providing blood samples and completing surveys. Both groups will have regular visits to the clinic for blood work, body measurements, sleep and activity tracking, quality-of-life questionnaires, and dietary assessments. The study will monitor your liver function, blood sugar levels, metabolism, and how you're feeling throughout your participation.

AI-generated summary from trial data · Jul 4, 2026 · Not medical advice

Time-restricted eating and healthy diet for liver disease and cancer patients

What is this trial?

Do you qualify?

What participation looks like

Trial locations