Plain-English translation of NCT06829238 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether can help repair immune system damage in adults who have a history of injecting drugs. Researchers believe that may reduce harmful inflammation and help the immune system respond better to vaccines. You would receive this medication for 16 weeks while also getting two protective vaccines.
People with a history of injection drug use often have weakened immune systems that don't respond well to vaccines, even those with HIV who are doing well on treatment. This study is exploring whether this common, affordable medication could help restore immune function and make vaccines more effective in this population.
You likely qualify if…
You likely don't qualify if…
You would take the medication by mouth for 16 weeks, starting at a lower dose and gradually increasing it. During this time, you would receive two vaccines to help your immune system fight infections. You would have blood drawn multiple times over 6 months so researchers can measure how your immune system is responding and check that the medication is safe for you.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States