Plain-English translation of NCT06831409 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
The GAMEFILM Registry is a research study that uses a special type of heart imaging called CTA (computed tomography angiography) to look for signs of heart disease in retired NFL players. Researchers want to understand how often heart disease occurs in this group and how severe it tends to be. This information could help doctors better identify and treat heart problems in former athletes.
Heart disease is a leading cause of death, and some research suggests that retired NFL players may have different risks than the general population. By screening this group and collecting their health information, researchers hope to better understand these risks and improve how doctors care for former athletes' heart health.
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If you join this study, you will have a heart CT scan performed at one of about 20 study locations across the United States. The scan uses computer imaging to take detailed pictures of your heart and blood vessels. This is a non-invasive test — no surgery or needles are involved — and typically takes less than 15 minutes. Your scan images will be analyzed using special computer software to look for signs of heart disease.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
United States
Enrollment target
~300 participants
Started
December 2024
Primary completion
December 2026
Last updated on clinicaltrials.gov in August 2025.
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Central contact
HeartFlow
Boone Heart Institute
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