Plain-English translation of NCT06835283 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This pilot study is testing a new combination treatment for behavioral and emotional symptoms in Alzheimer's disease using two types of non-invasive brain stimulation: iTBS (intermittent theta burst stimulation) and tDCS (transcranial direct current stimulation). Both use gentle magnetic or electrical pulses to stimulate the brain without surgery or pain. Researchers want to see if combining these two treatments works better than either one alone, and whether the approach is practical for patients and their caregivers.
Many people with Alzheimer's disease struggle with mood swings, apathy, and agitation that don't respond well to current medications or cause unwanted side effects. This trial exists to explore whether brain stimulation might offer a safer, more effective option for managing these difficult symptoms.
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If you enroll, you would receive one week of in-clinic brain stimulation sessions (5 days in a row) using magnetic pulses, then spend 4 weeks at home using a portable device to deliver electrical stimulation daily. Throughout the study, you'll have brain scans and complete questionnaires to help researchers track any changes in your symptoms and brain activity. Your caregiver will play an important role by accompanying you to clinic visits and helping you with the at-home treatment sessions.
AI-generated summary from trial data · Jul 1, 2026 · Not medical advice
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