Plain-English translation of NCT06837922 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Asthma research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing a new medication called MG-K10, which is a humanized monoclonal antibody given by injection every four weeks. The study will enroll 504 teenagers and adults with moderate-to-severe asthma to see whether this treatment helps control their symptoms better than a placebo (inactive injection). Half the participants will receive the medication and half will receive placebo injections, and no one will know which group they're in.
Many people with asthma still struggle with symptoms and flare-ups even when taking standard inhaled medications and other treatments. This medication is being tested to see if it can provide better control for those whose asthma remains difficult to manage.
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The study lasts about 5 months total: a 1-week screening period, a 4-week lead-in period where researchers observe your baseline asthma, 52 weeks of treatment with injections every 4 weeks, and an 8-week follow-up. You will receive either the new medication or a placebo injection at regular clinic visits, and you'll complete breathing tests and answer questions about your asthma symptoms throughout the year to see whether the treatment improves your control.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
China
Phase
Large-scale testing
Sponsor
Shanghai Mabgeek Biotech.Co.Ltd
Enrollment target
~504 participants
Started
March 2025
Primary completion
November 2027
Age range
12 Years – 75 Years
Last updated on clinicaltrials.gov in April 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
lipeng.liu L lipeng.liu, bachelor 02151371305 lipeng.liu@mabgeek.com, bachelor
The First Affiliated Hospital of Guangzhou University of Medical
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.