Plain-English translation of NCT06840886 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This study is testing a new experimental medication called in people with advanced solid tumors (cancers) that have come back or stopped responding to standard treatments. The trial starts by testing alone at different dose levels to find the safest and most effective dose, then later tests it combined with chemotherapy drugs. Researchers will track how your body handles the medication and whether it helps shrink tumors.
Many people with advanced cancers run out of standard treatment options, and their cancers continue to grow. This medication targets a protein on cancer cells that hasn't been tested in humans before, and this trial aims to find out if it's safe and whether it can help control these hard-to-treat cancers.
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You will visit the research clinic regularly for physical exams, blood tests, and imaging scans to monitor your health and how the cancer responds. The first part of the trial involves starting at a low dose of the medication and gradually increasing it to find the safest level — some participants may receive only the new medication, while others later in the trial will receive it combined with standard chemotherapy drugs. The study continues until the researchers find the best dose and determine whether the treatment is working for your cancer type.
AI-generated summary from trial data · Jun 23, 2026 · Not medical advice
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