Recruiting

Stem cell treatment to restore fertility in men and women

Plain-English translation of NCT06841328 on ClinicalTrials.gov ↗ · Source last updated April 2025 · Translation generated August 2026 · How we translate trials

What is this trial?

This trial is testing stem cell injections—specifically cells derived from fat tissue or their byproducts—to help restore fertility in people whose ovaries or testes have failed. The treatment is designed to repair damaged tissue and restart natural hormone and sperm or egg production. This approach offers hope for people who haven't responded well to standard hormone treatments or surgery.

Standard treatments like hormone therapy help ease symptoms but don't restore the ability to have children naturally. Surgery to retrieve sperm or eggs carries risks and isn't always successful. This trial exists to explore whether the new treatment might offer a safer, less invasive way to help reproductive organs work again.

Do you qualify?

You likely qualify if…

you are between 20 and 50 years old
you have been diagnosed with testicular failure, low testosterone, or no sperm production (men) OR premature ovarian failure or ovarian insufficiency (women)
you have tried standard treatments like hormone therapy and they did not work well enough for you
you are in generally good health without serious heart, kidney, or uncontrolled diabetes conditions
you are willing to consent to the study and follow all study instructions

You likely don't qualify if…

you have severe heart disease, kidney failure, or uncontrolled diabetes
you have ever had cancer or have a current cancer diagnosis within the past 5 years
you are currently taking blood thinners or medications that might interfere with stem cell therapy
you have had recent ovarian or testicular surgery or injury that could affect results
you have participated in another experimental treatment study within the past 6 months

What participation looks like

You would visit the clinic for a stem cell or exosome injection directly into your ovaries or testes, a procedure done with ultrasound guidance. The trial will track your safety and measure whether your fertility improves, hormone levels normalize, and sperm or egg production restarts. You'll need to follow the study protocol and attend follow-up visits so the research team can monitor your response to the treatment over time.

AI-generated summary from trial data · Aug 22, 2026 · Not medical advice

Trial locations(1 site)

United Arab Emirates

First IVF and Day Surgery Center, Dubai, Dubai