Plain-English translation of NCT06841692 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
This study doesn't follow the usual testing phases โ it may be an observational study or a different type of research.
Researchers want to know if a diagnostic test using two water pills โ bumetanide and hydrochlorothiazide โ can predict whether someone's chronic kidney disease will get worse over time. This test involves giving these medications and then collecting blood and urine samples to see how your kidneys respond. The study will compare how people with kidney disease react to this test versus how healthy people react.
Chronic kidney disease affects many people, but doctors currently have limited ways to predict who will experience faster decline in kidney function. This medication test could help doctors identify which patients need more aggressive treatment or closer monitoring earlier on.
You likely qualify ifโฆ
You likely don't qualify ifโฆ
You will come in for a test day where you receive the two water pill medications. Blood and urine samples will be collected before and after taking the medications to measure how your kidneys handle them. You may also have a comparison group of healthy volunteers tested the same way, so researchers can see the difference between healthy and diseased kidneys. The visit is one-time, though you should expect to be at the clinic for several hours for the testing and sample collection.
AI-generated summary from trial data ยท Jun 24, 2026 ยท Not medical advice
Netherlands