Plain-English translation of NCT06846086 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether melatonin, a natural substance your body makes, can help protect and improve heart function in people with cardiomyopathy. Half of the participants will take melatonin as an add-on to their regular heart medications, while the other half will continue with standard treatment alone. The study will last 3 months and will measure whether the medication helps your heart work better and reduces symptoms.
Cardiomyopathy is a serious condition where the heart muscle weakens over time, and current medicines help slow it down but don't fully stop the damage. Early research suggests this medication may protect heart cells from damage by reducing harmful inflammation and strengthening the energy-producing parts of your cells, offering hope for a better treatment option.
You likely qualify if…
You likely don't qualify if…
If you enroll, you'll be randomly assigned to either take the medication as a daily pill along with your regular heart medications, or to continue with your standard treatment alone. The study lasts 3 months, during which you'll likely have clinic visits to check your heart function, blood work, and how you're feeling. Your doctors will monitor whether the medication is helping your symptoms and protecting your heart.
AI-generated summary from trial data · Jul 19, 2026 · Not medical advice
Egypt
Phase
Large-scale testing
Sponsor
Tanta University
Enrollment target
~46 participants
Started
February 2025
Primary completion
January 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Reem Alaa, Bachelor of Pharmacy (2023)
Tanta University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.