Plain-English translation of NCT06848309 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand how your immune system fights off flu and COVID-19 infections. This study will collect blood, saliva, and nasal samples from people who currently have flu or COVID-19 symptoms, as well as from people who have been vaccinated but never had these infections. By studying these samples over six months, scientists hope to learn why some people get sicker than others and how vaccination affects the body's ability to fight these viruses.
When people get the flu or COVID-19, their bodies mount an immune response to fight the virus, but we don't fully understand how this works or why vaccinated people sometimes still get infected. This research could help doctors predict who will have severe illness and improve future vaccines.
You likely qualify if…
You likely don't qualify if…
If you join this study, you'll visit the clinic five times over six months—at the start, one week later, between 10–28 days after enrollment, at three months, and at six months. At each visit, researchers will collect blood samples, saliva, and nasal swabs to track how your immune system responds to the infection. Some participants may be invited to take part in an optional additional procedure involving a bronchoscopy (a camera inserted into the lungs) and chest X-rays, but this is not required to participate.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States