Plain-English translation of NCT06852352 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Alzheimer Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial investigates a surgical procedure called deep cervical lymphovenous anastomosis (LVA) as a potential treatment for Alzheimer's and Parkinson's disease. The procedure aims to improve how the brain drains waste products and toxic proteins that build up over time. Researchers believe this treatment could slow disease progression and help preserve thinking and movement abilities.
In both Alzheimer's and Parkinson's disease, harmful proteins accumulate in the brain and contribute to nerve cell damage. As we age, the brain's natural drainage system becomes less efficient, allowing these toxic proteins to build up. This trial explores whether restoring the brain's waste clearance system through this surgical technique could reduce protein buildup and slow disease progression.
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If you enroll, you will receive the surgical procedure to connect lymphatic vessels in your neck, designed to improve brain drainage. Over the following 24 months, you will return for regular visits to undergo brain imaging (MRI and PET scans), provide blood and spinal fluid samples for protein analysis, and complete tests to measure thinking and movement abilities. The study team will track whether the procedure helps slow your disease and improves your quality of life.
AI-generated summary from trial data · Jul 16, 2026 · Not medical advice
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