Testing a new skin cream for eczema

Plain-English translation of NCT06855745 on ClinicalTrials.gov ↗ · Source last updated August 2025 · Translation generated June 2026 · How we translate trials

Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.

What is this trial?

This trial is testing a new medication called hydrogel to see if it can help improve eczema (atopic dermatitis) when applied directly to the skin. About 72 people with mild to moderate eczema will participate across 10 Australian sites. Half will receive the new treatment, and half will receive a placebo (inactive cream) to compare how well the medication works.

Eczema can cause itching, irritation, and discomfort that affects daily life. This study aims to find out whether this new topical treatment is safe and effective at reducing eczema symptoms in people who haven't found sufficient relief with other options.

Do you qualify?

You likely qualify if…

you are at least 2 years old
you have been diagnosed with eczema for at least 6 months (3 months if you're under age 6)
your eczema is mild to moderate in severity
your eczema covers at least 2% but no more than 20% of your body surface area
you have itching that rates at least 4 out of 10 on a pain scale
you are willing to avoid other topical products on your eczema during the study

You likely don't qualify if…

your eczema is rapidly getting worse or suddenly improving on its own
you have other skin conditions that could interfere with evaluating the eczema
you have eczema only on your hands or feet without a history of involvement elsewhere
you are currently taking or planning to take other systemic or topical treatments that could affect your eczema
you have had UV light therapy or significant sun exposure in the 2 weeks before screening

What participation looks like

You will apply either the new medication or placebo cream to your eczema patches twice daily for 16 weeks. You'll visit the study site every 2 weeks for the first month, then monthly until the end of the study. At each visit, the study team will examine your skin using a standard assessment scale to track how your eczema responds to treatment.

AI-generated summary from trial data · Jun 3, 2026 · Not medical advice

Trial locations(12 sites)

Australia

Canopy Clinical Northern Beaches, Brookvale, New South Wales

Momentum Clinical Research, Darlinghurst, New South Wales

Premier Specialists, Kogarah, New South Wales

St George Dermatology, Kogarah, New South Wales

Novatrials, Kotara, New South Wales