Plain-English translation of NCT06861452 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing a new treatment called for people with locally advanced pancreatic cancer. is made from your own fat cells that have been specially modified in the lab to fight cancer. You would first receive two cycles of standard chemotherapy drugs, and then doctors would inject the modified cells directly into your tumor to help your body kill the cancer cells.
Most people with advanced pancreatic cancer cannot have surgery to remove the tumor, which is currently the only treatment that might cure it. This study is looking for new ways to help more patients become healthy enough for surgery, or to improve their outcomes when surgery is not possible.
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You would receive chemotherapy injections over two months (two cycles given on specific days each month), with regular clinic visits and blood tests to monitor your health. After completing the chemotherapy, you would have a minor liposuction procedure to collect fat from your body. Your fat cells would then be sent to a lab to be modified into the new treatment, which would be injected directly into your pancreatic tumor during a guided procedure. You would then return for follow-up visits and imaging scans to see how your body responds to the treatment.
AI-generated summary from trial data · Sep 20, 2026 · Not medical advice
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