Plain-English translation of NCT06861790 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers are studying how weight loss surgery affects your brain and memory, and whether a non-invasive nerve stimulation device called transcutaneous vagal nerve stimulation (tVNS) can improve those effects. You'll be getting weight loss surgery as part of your regular medical care, and this study will track changes in your brain, thinking, and memory over 18 months using brain scans and memory tests.
Weight loss surgery helps people lose weight and control diabetes, but doctors don't fully understand how it changes brain function and whether adding nerve stimulation might make those benefits even better. This research could lead to better outcomes for people with obesity and type 2 diabetes.
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You will have memory and thinking tests at the start, after 12 weeks, and again at 18 months. You'll receive the assigned treatment during your weight loss surgery—either nerve stimulation or a placebo version—and use a small device at home for 30 days after surgery. You'll also have brain MRI scans and blood tests at each visit to measure changes in your brain, blood sugar levels, and other health markers.
AI-generated summary from trial data · Jul 1, 2026 · Not medical advice
United States