Plain-English translation of NCT06864130 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether women with osteoporosis can safely stop taking alendronate after they've been on it for several years without breaking any bones. Right now, doctors aren't sure if women need to keep taking this medication forever, or if they can stop it after a certain point. The study will track whether women who stop the medication have more fractures than those who keep taking it.
Many women take bone-strengthening medications for years, but doctors don't know if long-term treatment is always necessary, especially if someone hasn't had any fractures. This trial aims to answer whether it's safe to stop this medication after a fracture-free period, which could help women avoid unnecessary long-term treatment.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to either continue taking the medication once a week or stop taking it entirely. Over three years, you'll visit the clinic for bone density scans and blood tests at the start, then at 1, 2, and 3 years, with additional blood draws at 6 and 18 months. The study will carefully monitor whether you develop any fractures and how your bones change over time.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
Denmark