Plain-English translation of NCT06864195 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
The VOCAL2 study is developing a non-invasive breath test that analyzes tiny chemicals in your exhaled breath to help detect liver cancer earlier and monitor liver conditions like cirrhosis. Right now, liver cancer is often caught too late for effective treatment, so researchers are testing whether this simple breath test could be a game-changer. The test is safe, quick, and requires no needles or invasive procedures.
Liver cancer is frequently diagnosed at advanced stages when treatment options are limited. This study aims to create an easier, earlier way to detect liver cancer and monitor related liver diseases, which could significantly improve patient outcomes.
You likely qualify if…
You likely don't qualify if…
If you join, you'll visit an NHS hospital for about one hour. You'll fast for 6 hours beforehand, then provide a breath sample into a collection device—that's it. You'll also answer some health questions and allow the research team to access your relevant medical records. There are no needles, no medications to take, and no ongoing visits required.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
United Kingdom
Enrollment target
~750 participants
Started
February 2025
Primary completion
January 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Georgios Karagiannidis, MBBS(Hon)
Imperial College London
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.