Plain-English translation of NCT06868160 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether combining gentle electrical stimulation of the brain and spine with specialized walking and balance training can help people with Parkinson's disease who struggle with posture and gait. Some participants will receive the training with real electrical stimulation, while others will receive the same training with sham (fake) stimulation, so researchers can see if the stimulation actually makes a difference. The study will measure changes in walking, balance, thinking ability, and brain activity using brain imaging and other assessments.
Walking and balance problems are common and disabling in Parkinson's disease and don't always improve well with medication alone. Researchers believe that combining specialized training with non-invasive electrical stimulation might help the brain form new connections and improve motor recovery more effectively than training alone.
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You will visit the research center multiple times over 28 weeks. At the start, you'll have brain imaging (MRI), brain activity monitoring (EEG and fNIRS), blood tests, and assessments of your walking, balance, and thinking. Then you'll participate in two 6-week training cycles separated by an 8-week break, attending sessions 3 times per week for about 1 hour each. Each session combines watching and imagining movements with practicing walking and balance exercises, plus either real or sham electrical stimulation depending on your group assignment. At the end, you'll repeat some of the initial assessments to see if things have improved.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
Italy