Plain-English translation of NCT06869811 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a combination approach — adding a left atrial appendage occlusion device (a small implant that closes off a pouch in the heart where clots can form) plus continued blood thinner medication — can better prevent future strokes. You may be a good candidate if you've had a stroke even while taking blood thinners for an irregular heartbeat. The study will compare this combined treatment to the best medical care your doctor recommends, which might include changing or intensifying your blood thinner medication.
Some people continue to have strokes even while taking blood thinner medications, and doctors don't yet have clear guidelines on the best way to prevent future strokes in these patients. This trial exists to see whether adding a heart device to blood thinner medication offers better protection than medication changes alone.
You likely qualify if…
You likely don't qualify if…
If you join this trial, you will be randomly assigned to one of two groups: one group will receive the best medical treatment (which may include changing blood thinner medications), and the other will receive a left atrial appendage occlusion device plus blood thinner medication. The device procedure involves a catheter (thin tube) inserted through a blood vessel, and you will need imaging tests (CT or ultrasound) beforehand to prepare. You'll visit the hospital for the procedure and return for follow-up visits over 12 months, with the main focus being whether you have any new strokes or blood clots during that year.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
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